There are two barriers to ocular drug adsorption: (a) the blood–aqueous barrier and (b) the blood–retina barrier. The blood–aqueous barrier is composed of the ciliary epithelium, the epithelium of the posterior surface of the iris, and blood vessels within the iris
Disintegrants are materials that are added to tablet and hard gelatin capsule formulations to aid in the breakup of a tablet or granules after oral administration. Disintegrant rapidly takes up water and breaks apart the formulation
Binders are materials that are added to impart cohesiveness to the drug and excipient combination during the formulation of an oral solid dosage form. Cohesiveness not only assists in the formation and flow of granules
Although nasal route is traditionally used for locally acting drugs, this route is getting more attention for the systemic delivery of various peptide drugs that are poorly absorbed via the oral route.
VOLINI GEL should be rubbed gently into the skin. Depending on the size of the affected site to be treated 2-4g (a circular shaped mass approximately 2.0-2.5cm in diameter) should be applied 3-4 times daily.
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