chloramphenicol eye drops

ABCHLOR (Chloramphenicol) eye drops B.P

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ABCHLOR eye drop contains an antibiotic called chloramphenicol. Chloramphenicol is a broad spectrum bacteriostatic antibiotic originally isolated from Streptomyces venezuelae, which has activity against many types of Gram-positive and Gram-negative bacteria. Acute bacterial conjunctivitis is commonly caused by Staphylococci or Streptococci in adults and Haemophilus influenza and Moraxella catarrhalis particularly in children. It has minimal resistance to Staphylococci and many other species of bacteria

It interferes with the step of transferring activated amino acids from soluble RNA to ribosomes during protein synthesis. It binds to the 50s ribosomal subunit and thereby prevents the formation of the peptide bond. This leads to inhibition of further multiplication of the bacteria.

chloramphenicol eye drops

Indications

ABCHLOR eye drops are used for the treatment of bacterial conjunctivitis due to susceptible micro-organisms. The infected eye will probably be red, gritty or itchy. ABCHLOR eye drops will help kill the infective bacteria and allow the eye to overcome the infection

Dosage

Two drops topically in the affected eye, every three hours or use as directed by a physician.

Contraindications

ABCHLOR is contraindicated in those patients who may be hypersensitive to any of its components. As with all eye preparations, containing Phenyl mercuric nitrate, those using the drops should not wear soft contact lenses during treatment.

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Precautions

Prolonged use of antibiotics may occasionally result in overgrowth of non-susceptible organisms, including fungi. If new infections appear during treatment, the drug should be discontinued and appropriate measures should be taken. In some circumstance this medicine may not be suitable for you. If you are pregnant o intending to become pregnant. If you are breast feeding a baby

Drug interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of nay medicine before checking with them first. Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use. Keep a list of all your medications with you and share the list with your doctor and pharmacist.

Side-effects

A burning or stinging sensation for a short while after using the drops. When there is prolonged irritation, pain, swelling, watery eye or sensitivity to light, then the exposed eye should be washed with water for 15 minutes. If the symptoms continue after this, an eye examination may be required.

Composition

  • Chloramphenicol B.P 0.5%W/V
  • Phenyl mercuric nitrate B.P (as preservative) 0.002%w/v
  • Aqueous vehicle q.s
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