Absorbable surgical suture, Catgut
TRUGUT is a sterile absorbable surgical suture composed of purified connective tissue (collagen) from sub-mucous layer of sheep (bovine) intestine. Trugut is available as plain & chromic and in range of gauge sizes and lengths, non-needled or attached to stainless steel needles of varying types and sizes
Trugut chromic is a suture which has been tanned by treatment with chromium salt in the trivalent form and colored with oxidized Pyrogallol, colour index number 76515, to prolong its resistance to absorption and to colour the material dark brown. Trugut complies with the requirements of the European Pharmacopeia Monograph for “sterile catgut” and the United States Pharmacopeia for “absorbable surgical suture”
Trugut is indicated for use in soft tissue approximation and or ligation, including use in plastic and ophthalmic procedures but not for use in cardiovascular and neurological tissues.
Sutures should be selected and implanted depending on patient condition, surgical experience, surgical technique and wound size. When trugut suture is implanted, a moderate tissue inflammation occurs which is characteristic of a foreign body response. Loss of tensile strength and loss of suture mass flows as the proteolytic enzymatic digestive process proteolyse the surgical catgut.
Due to the inherent variability of a natural material, figures for strength loss and absorption following implantation are for guidance only. Effective strength is usually lost between 10 to 12 days in case of plain catgut and by 21-30 days in case of chromic catgut. Absorption is essentially complete by 60-90 days. In humans, various factors may affect the tensile strength loss and rate of absorption.
Two of the major factors are: infection and tissue site Trugut is absorbed more rapidly in infected tissues than in non-infected tissues. Trugut is absorbed more rapidly in tissues where increased levels of proteolytic enzymes are present as in the secretions from the stomach, cervix and vagina
Trugut sutures, being absorbable, should not be used where extended approximation of tissues under stress is required. Trugut (chromic) is contraindicated in patients with known sensitivities or allergies to collagen or chromium since chromic catgut is a collagen based material which has been treated with chromic salt material.