ACRASON CREAM

ACRASON CREAM

Share this
Advertisement

ACRASON CREAM

Betamethasone dipropionate is a potent topically active corticosteroid producing prompt, marked and prolonged anti-inflammatory, antipruritic and vaso-constrictive effects.

Clotrimazole is a broad spectrum, antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic Dermatophytes, Yeast and Malassezia furfur.

Gentamicin sulfate, a wide spectrum antibiotic, provides highly effective topical treatment in primary and secondary bacterial infections of the skin.

Composition

Each gram contains:

  • Betamethasone dipropionate 0.64 mg
  • Clotrimazole 10 mg
  • Gentamacin sulfate 1 mg (potency)

Indications

  1. Allergic inflammatory dermatoses: acute chronic eczenmas, contact dermatitis, atopic dermatitis, siborrheic dermatitis, alphosis, itching (anus, mons veris), solar dermatitis, etc.
  2. Alopecia, first-degree burn, area affected by insects, secondary bacterial infectious dermatoses.
  3. Dermatophytoses: ringworm, athlete’s foot, etc.

Dosage and administration

Apply to the affected area once or several times daily.

Cautions

  • If this drug is used to the wide are with massive amount for a long time (especially occulsive dressing therapy), it may cause the same symptoms as adrenal corticosteroids when used systemically.
  • It may cause the topical adverse reactions like dermatrophia, steroidal ruber etc. After deep consideration, apply for rash on facies, neck, genital or intertrigo
  • If the symptoms improve, change into another mild topical therapy as soon as possible
  • Do not use to the sensitized patients.
  • Do not use it continuously for a long period.

Contraindications

  • Do not apply to the affected area or mucous membrane.
  • A patient with tubercular skin, herpes simplex, varicella, herpes zoster, vaccinia or syphilis.
  • A patient who is hypersensitive to this drug
  • A patient with otopolypus eczematosa with perforating myrinx.
  • A patient with skin ulcer.
  • A patient with a history of hypersensitive to the aminoglycosidic antibiotics (including streptomycin, neomycin, kanamycin, gentamacin, etc.) or bacitracin.

Adverse reactions

Skin:

  • Long-term use may cause steroidal acne, steroidal skin (dermatrophia, angiotelectasis), or perioal dermatoses (perioral or facial ruber, papule, angiotelectasis, crusta, Iodiculae, etc.)
  • It may cause ichthyosiform, pelloma, pilosis, incontenentia pigmenti, etc.
  • If these symptoms appear, reduce the dose gradually and change into another drug excluding adrenal cortical steroids.

Hypersensitivity:

  • Skin irritation, rash, etc. may occur. If these symptoms occur, discontinue the use

Adrenalcorticoidal system,hypophysis: if this drug is used to the wide area it may cause the functional inhibition.

Eye:

  • If this drug is used to the blepharon, it may cause intraocular hypertension
  • If this drug is used to the wide area with massive amount for a long time (especially occulsive dressing therapy), it may cause cataract, glaucoma, etc.

Pregnancy: Teratogenesis has been reported in animal test. It is recommendable not to use to a pregnant woman or a woman who is going to be pregnant.

Pediatric use: this drug may cause dysgenesis. If used massively for a long time or with the occulsive dressing therapy (ODT). The diaper may induce the same reaction as ODT.

Precautions

  1. Do not use for the ophthalmic demands
  2. This drug includes propylene glycol ( a inactive ingredient). If a patient is hypersensitive to this substance, consult a doctor before the use.
Advertisement
Share this

Leave a Comment

Your email address will not be published. Required fields are marked *