Betamethasone dipropionate is a potent topically active corticosteroid producing prompt, marked and prolonged anti-inflammatory, antipruritic and vaso-constrictive effects.
Clotrimazole is a broad spectrum, antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic Dermatophytes, Yeast and Malassezia furfur.
Gentamicin sulfate, a wide spectrum antibiotic, provides highly effective topical treatment in primary and secondary bacterial infections of the skin.
Each gram contains:
- Betamethasone dipropionate 0.64 mg
- Clotrimazole 10 mg
- Gentamacin sulfate 1 mg (potency)
- Allergic inflammatory dermatoses: acute chronic eczenmas, contact dermatitis, atopic dermatitis, siborrheic dermatitis, alphosis, itching (anus, mons veris), solar dermatitis, etc.
- Alopecia, first-degree burn, area affected by insects, secondary bacterial infectious dermatoses.
- Dermatophytoses: ringworm, athlete’s foot, etc.
Dosage and administration
Apply to the affected area once or several times daily.
- If this drug is used to the wide are with massive amount for a long time (especially occulsive dressing therapy), it may cause the same symptoms as adrenal corticosteroids when used systemically.
- It may cause the topical adverse reactions like dermatrophia, steroidal ruber etc. After deep consideration, apply for rash on facies, neck, genital or intertrigo
- If the symptoms improve, change into another mild topical therapy as soon as possible
- Do not use to the sensitized patients.
- Do not use it continuously for a long period.
- Do not apply to the affected area or mucous membrane.
- A patient with tubercular skin, herpes simplex, varicella, herpes zoster, vaccinia or syphilis.
- A patient who is hypersensitive to this drug
- A patient with otopolypus eczematosa with perforating myrinx.
- A patient with skin ulcer.
- A patient with a history of hypersensitive to the aminoglycosidic antibiotics (including streptomycin, neomycin, kanamycin, gentamacin, etc.) or bacitracin.
- Long-term use may cause steroidal acne, steroidal skin (dermatrophia, angiotelectasis), or perioal dermatoses (perioral or facial ruber, papule, angiotelectasis, crusta, Iodiculae, etc.)
- It may cause ichthyosiform, pelloma, pilosis, incontenentia pigmenti, etc.
- If these symptoms appear, reduce the dose gradually and change into another drug excluding adrenal cortical steroids.
- Skin irritation, rash, etc. may occur. If these symptoms occur, discontinue the use
Adrenalcorticoidal system,hypophysis: if this drug is used to the wide area it may cause the functional inhibition.
- If this drug is used to the blepharon, it may cause intraocular hypertension
- If this drug is used to the wide area with massive amount for a long time (especially occulsive dressing therapy), it may cause cataract, glaucoma, etc.
Pregnancy: Teratogenesis has been reported in animal test. It is recommendable not to use to a pregnant woman or a woman who is going to be pregnant.
Pediatric use: this drug may cause dysgenesis. If used massively for a long time or with the occulsive dressing therapy (ODT). The diaper may induce the same reaction as ODT.
- Do not use for the ophthalmic demands
- This drug includes propylene glycol ( a inactive ingredient). If a patient is hypersensitive to this substance, consult a doctor before the use.