Paracetamol has analgesic and antipyretic actions. It is rapidly absorbed from the gastrointestinal tract, conjugated in the liver to glucuronide or sulphate metabolites and predominantly excreted in the urine, within 24 hours.
Relief of pain and fever due to conditions such as headache, colds, influenza, musculoskeletal conditions and dysmenorrhea. It is suitable for both adults and children and is useful as an analgesic for patients with dyspepsia, ulcers and gout.
Dosage and administration
As indicated by the physician or pharmacist:
Adults: 500 mg to 1g (one to two tablets)
Children: 1 to 6 years: 125-250 mg (1/4 – ½)
6 to 12 years: 250 to 500 mg These doses may be taken three or four times a day.
Children: 3 months – 1 year: 2.5 – 5 mil
1 – 6 years: 5 – 10 mil
6 – 12 years: 10 – 20 mil The appropriate doses may be given three or four times a day. Administration to infants under 1 months is not recommended.
Dyspepsia, nausea or allergic reactions occur rarely. Hematological reactions including thrombocytopenia, leucopenia, pancytopenia and agranulocytosis have been reported.
Paracetamol should be given with care to patients with impaired kidney or liver function.