pregabalin

PREGABALIN (25Mg/50Mg/75Mg/150Mg/300Mg capsules)

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PREGABALIN (25Mg/50Mg/75Mg/150Mg/300Mg capsules)

Active substance: Lactose anhydrous USP, Pregelatinized starch USP, Talc USP.

Indications and usage

Management of neuropathic pain associated with diabetic peripheral neuropathy

Management of post herpetic neuralgia

Adjunctive therapy for adult patients with partial onset seizures

Management of fibromyalgia

Contraindications

Pregabalin is contraindicated to known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy.

Dosage and administration

Pregabalin is given orally with or without food. The maximum recommended dose of pregabalin is 100mg three times.

Precautions

  • Angioedema- can cause angioedema
  • Hypersensitivity- skin redness, blisters, hives, rash, dyspnea and wheezing.

Withdrawal of Antiepileptic Drugs( AEDs)

As with all AEDs, withdraw pregabalin gradually to minimize the potential of increased seizure frequency in patients with seizure disorder.

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  • Suicidal Behavior and ideation- Antiepileptic drugs(AEDs) including pregabalin increase the risk of suicidal thoughts
  •  Peripheral edema- can cause peripheral edema  
  •  Dizziness and Somnolence
  •  Weight gain- can cause weight gain 
  •  Decreased platelet count – can lead to decreased blood platelet

Side effects

Dizziness and Somnolence

Headache

Ataxia

Asthenia

Dry mouth

Constipation

Edema

Blurred vision

Weight gain

Thinking abnormally

Storage

Keep out of reach of childrenprotect from light and mixtureStore below 30°c in dry place




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