Pharmacogenomics uses information about a person’s genetic makeup, or genome, to choose the drugs and drug doses that are likely to work best for that particular person. This new field combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.
Vaginal epithelium is permeable to a wide range of substances, including steroids, prostaglandins, antibiotics, estrogens, and spermicidal agents. Most steroids are readily absorbed by vaginal epithelium, leading to their higher bioavailability
Natural compounds extracted from plants have often provided novel structures for therapeutic applications. For example, vincristine is derived from the periwinkle plant Vinca rosea, etoposide is from the mandrake plant
Regulation and control of new drugs in the United States are the responsibilities of the federal FDA (http://www.fda.gov).
The chemical name is the only one that describes unambiguously the chemical structure of a drug, identifying it fully and exactly. It is given according to rules of nomenclature of chemical compounds.
Today, natural sources are still important, but the majority of lead compounds are synthesized in the laboratory
Drugs find their way into therapeutics mainly by one of the following routes: serendipity, random screening, extraction of active principles from natural sources,