Climara Pro® (estradiol/levonorgestrel transdermal system)
Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics.
menopause
Postmenopausal vaginal bleeding
Postmenopausal bleeding is bleeding that occurs after menopause. Menopause is a stage in a woman’s life (around age 51) when reproductive hormones drop and her monthly menstrual periods stop.
Menostar® (estradiol transdermal system)
Menostar (estradiol transdermal system) is designed to provide nominal in vivo delivery of 14 mcg of estradiol per day continuously upon application to intact skin. The period of use is 7 days
BRISDELLE® (paroxetine) capsules
BRISDELLE (paroxetine) is an orally administered selective serotonin reuptake inhibitor (SSRI) for the treatment of moderate to severe VMS associated with menopause.
ORIAHNN (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules)
ORIAHNN is a combination of elagolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist, estradiol, an estrogen, and norethindrone acetate, a progestin, indicated for the management of heavy menstrual bleeding associated with uterine leiomyomas (fibroids) in premenopausal women.
The End of Reproductive Life in Women
The reliability of ovarian function, both hormonally and reproductively, peaks in the mid-to-late twenties. Beginning in the early thirties, there is epidemiologic evidence of a decline in fertility