ORODAR/ Sulfadoxine & Pyrimethamine (SP)
ORODAR/ Sulfadoxine & Pyrimethamine (SP). Sulfadoxine is a long acting sulphonamide which inhibits production of nucleic acids in sensitive micro-organisms including the malaria causing plasmodium species. Pyrimethamine is an antimalarial drug which inhibits the enzyme dihydrofolate reductase essential in the production of nucleic acids in the parasite.