COPD, or chronic obstructive pulmonary disease, is a serious lung disease that over time makes it hard to breathe. Other names for COPD include chronic bronchitis or emphysema. COPD, a leading cause of death, affects millions of Americans and causes long-term disability.
Salbutamol is a selective β-2 adrenoceptor agonist. It has very little or no action on the β-1 receptors of the heart. At therapeutic doses, salbutamol acts on the β-2 receptors of the bronchial muscle, the end effect being dilation of the bronchial airways through relaxation of bronchial smooth muscle and reduction of airway resistance.