BUNAVAIL contains buprenorphine, a partial opioid agonist, and naloxone, an opioid antagonist, and is indicated for the treatment of opioid dependence. BUNAVAIL should be used as part of a complete treatment plan that includes counseling and psychosocial support.
Naloxone is a semisynthetic opioid antagonist that competes with opioid analgesics for specific receptor sites in the central nervous system. Its effect, which persists for about 45 minutes, occurs within 1-2 minutes of intravenous administration.
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