Toto-mol® (Paracetamol suspension)

Share this
Advertisement

Aspirin free, OTC drug

Totomol® Suspension contains paracetamol, a potent analgesic and antipyretic agent used in the symptomatic management of pain and fever. Paracetamol has no anti-inflammatory effects. The analgesic effects of paracetamol is due to its action at pain receptors while its antipyretic effects depends on its ability to inhibit the hypothalamic prostaglandin synthetase system which results in the activation of heat loss mechanisms such as sweating and peripheral vasodilation and inhibition of thermogenesis.

toto-mol
Advertisement

Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 10 to 60 minutes after oral administration. It is well distributed into most body tissues and crosses the placenta and is present in breast milk. Paracetamol is metabolized predominantly in the liver and excreted in the urine mainly as the glucuronide and sulphate conjugates

Indications

Totomol® suspension is indicated in conditions where analgesic and antipyretic effects are desired. It is used in the management of mild to moderate pain such as headache, myalgia 9muscular pain) and dental pain.

The preparation is of value in the reduction of temperature in the treatment of minor febrile conditions, such as colds or influenza and in the symptomatic treatment of local redness, swelling, pain, and fever which may occur after immunization of children.

Dosage and administration

Totomol® suspension is administered by the oral route

Children under 1 year: half to 1 teaspoonful

Between 1 to 6 years: 1 to 2 teaspoonful

Between 7 to 12 years: 2 to 4 teaspoonful

In cases of post-immunisation pyrexia, a dose of 60mg is recommended for children 2 to 3 months of age. A second dose may be given after 4 to 6 hours; if the pyrexia persists after that dose, the parent should seek medical advice.

Precautions, warning and adverse effects

Totomol suspension should be administered with extreme caution to patients with impaired renal or liver function and patients taking other drugs that affect the liver

The side effects of paracetamol are usually mild, although haematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.

Resources

Share this

Leave a Comment

Your email address will not be published. Required fields are marked *

error: Content is protected !!