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Broad spectrum antifungal
Translipo-C contains clotrimazole which is an imidazole antifungal. It interferes with ergosterol synthesis and alters the cell membrane permeability of the cell membrane in sensitive fungi. Clotrimazole is fungistatic at concentrations achieved clinically.
Translipo-C has a wide spectrum of anti-microbial activity and it spectrum includes Candida species, epidermophyton, Histoplasma capsulatum,Trichophyton, furfur, microsporum. The protozoan Trachomonas vaginalis requires higher concentration for inhibition.
When applied topically Translipo C penetrates the epidermis but there is little if any systemic absorption. It is metabolized in the liver to inactive metabolites and it is excreted in the urine and faeces.
Indication
- Superficial candidiasis
- Dermatophytosis
- Napkin dermatitis
- Pityrias versicolor
- Trichomoniasis
- Serborrhoeic dermatitis
Pregnancy: This medication is not safe until the first trimester of pregnancy. However they should be used clearly under the supervision of a trained medical professional or doctor
Breast-feeding: This medicine is not recommended for breast-feeding women unless and until absolutely necessary
Ophthalmic use: This medicine is not to be used in the eyes
Vaginal irritation: This may cause burning or irritation on vaginal application
Resistance: This should be used for full prescribed course even if the symptoms get better
It is to be used with caution in patients with impaired renal and liver impairment. It is not to be used in pregnant women and breast feeding women.
Contraindications
It is to be contraindicated in women who are hypersensitive to ingredients such as clotrimazole.
Drug interactions: no specific drug interactions have been reported with the use of Translipo-C cream.
Dosage and administration: Translipo-C should be used 2-3 times daily for 2-4 weeks or as directed by the physician.
Possible side effects: Translipo-C may contain of the systemic side effects. Local side effects may include burning sensation along with contact dermatitis which may also occur
Resources
- https://www.1mg.com/drugs/translipo-c-cream-61147
- https://www.practo.com/medicine-info/translipo-c-1-cream-18994
- https://www.lybrate.com/medicine/translipo-c-1-cream
- https://www.medindia.net/drug-price/clotrimazole/translipo-c.htm
- https://www.ndrugs.com/?s=translipo%20-%20c
- https://www.medplusmart.com/product/TRANSLIPO-C-10GM-CREAM/TRAN0720
- https://www.netmeds.com/prescriptions/translipo-c-cream-10gm
- https://www.webmd.com/drugs/2/drug-4316/clotrimazole-topical/details
- https://www.nhs.uk/medicines/clotrimazole/
- https://my.clevelandclinic.org/health/drugs/18755-clotrimazole-skin-cream-lotion-or-solution
- https://www.medicines.org.uk/emc/product/2598/smpc
- https://www.just.edu.jo/DIC/AZLibrary/Clotrimazole%20cream.pdf
- https://pdf.hres.ca/dpd_pm/00031289.PDF
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020010s021lbl.pdf
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