Vasograin | Antimigraine tablets

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Vasograin is indicated for symptomatic relief in the acute attack of common migraine, classical migraine, menstrual migraine, cluster headache or histamine chephalagia and other vascular headaches.

 

Ergotamine Tartrate has marked vaso-constrictor action.


 

 

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Pharmaceutical ingredients

Ergotamine Tartrate has marked vaso-constrictor action. It is specific for the migraine attack and relieves the throbbing headache in more than 90% of the patients. It is most effective when given at the onset of headache.

Paracetamol is an analgesic, antipyretic drug. Simple analgesic like paracetamol are effective in migraine (Wilkison, 1976)

Caffeine provides a sense of wellbeing. When used in combination caffeine enhances the absorption and therapeutic efficacy of ergotamine tartrate (Schmiclt and Fanchamps, 1974)

Prochlorperazine is a phenothiazine derivative with potent antiemetic effects. It relieves nausea and vomiting which usually occurs at the peak of headache

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Dosage and administration

1 or 2 tablets in the beginning of the headache. One more after half an hour if necessary. In cluster headache one tablet of vasograin is recommended at bed time

Precautions

A dose of more than 4 tablets in a day or 10 tablets in a week should not be exceeded. Vasograin should not be used in patients with severe hypertension; peripheral, cerebral or coronary vascular disease, and impaired liver or renal function and in pregnancy. It can be used with caution in hypertensive patients with adequately controlled blood pressure

Side effects

Vasograin is usually well tolerated. Side effects due to ergotamine may occur in some patients. For example muscle cramps, stiffness, tiredness, numbness and paresthesis. Prolonged over dosage may lead to ergotism

 

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